University of Nebraska-Lincoln

  • 03 Nov 2015 11:28

AMAG Technology does its part in the fight against Terrorism at the University of Nebraska


The University of Nebraska-Lincoln, U.S.A Biological Process Development Facility (BPDF) is a leading facility in the research and development of processes to produce recombinant vaccines and biotherapeutic agents.

The BPDF focuses on biopharmaceutical process research, development, and manufacturing of vaccines and biotherapeutics derived from recombinants expression systems. They are recognized as the leading expert in the recombinant expression system, Pichia pastoris, which is used to express the botulism vaccines. UNL is one of the few universities working in the area of recombinant proteins for vaccines against various strains of botulism which was weaponized by Iraq in the early 1990s and posses a threat today. Othmer Hall is a brand new 133,000 square-foot four story building dedicated to chemical engineering. Othmer Hall was a component of a $125 million dollar donation to UNL by the Donald and Mildred Othmer Trust Fund. The BPDF has 11 distinct units located in Othmer Hall: Molecular Biology, Fermentation Development, Purification Development, Cell Culture Development, Analytical Methods, Protein Characterization, Quality Control-Chemistry, Quality Control- Microbiology, Master Cell Banking, cGMP Pilot Plant, and Quality Assurance. The BPDF houses all of its research and development laboratories on the third floor of Othmer Hall, with additional labs on both the first floor and lower level. The labs contain over $4 million worth of equipment, and priceless proprietary client documentation.

Download the complete Case Study: Nebraska-Lincoln